Digestive system 2This is a featured page


Learning Objectives
To understand the anatomy and functions of the accessory digestive organs. For more on the digestive system see Digestive System 1.

Notes, Pictures & Videos


The salivary glands, teeth, tongue, liver, gallbladder, and pancreas are not part of the digestive tract, but they have a role in digestive activities and are considered accessory organs.

Teeth and Supporting Structures

Teeth Types and Uses and X-rays:
Teeth are designed for eating: the incisors (the four front teeth) for biting, the canines (the eye teeth) for tearing, and the molars and premolars (back teeth) for chewing. The furthest back teeth (the third molars) are commonly known as the wisdom teeth and these do not usually appear in the mouth until the age of 17 to 21 years. These different teeth have evolved functions from both meat eaters such as tigers and lions, and grinders such as horses and cattle because we, and our teeth, are designed to eat both meat and vegetables. In other words, we are omnivorous. The adult mouth has the possibility of Thirty-Two teeth. Four of these are "wisdom teeth". Some people are missing adult teeth which is a congenital birth defect. Other people have extra adult teeth that cause problems and need to be removed. The best diagnostic tool is a panoramic x-ray to show all of the teeth and the jaws and the position of the joint. This can also diagnose cysts, tumors and trauma to the bones. Occlusal x-rays show just the upper jaw or lower jaw and teeth. This shows placement and amount of teeth. Especially used in children. Can also diagnose cysts, tumors and trauma. Individual tooth diagnosis is best when a PA or Periapical x-ray film is used.

Tooth Structure:
Each tooth has a pulp in the core which consists of nerves and blood vessels and this is surrounded by dentin, a hard bone-like substance which is itself covered with enamel over the crown. Enamel is the hardest tissue in the body and has no feeling in it. It is made of calcium crystals (hydroxyapatite), whereas the underlying dentin, which is in contact with the central nerves, is sensitive, and can be painful if exposed to hot or cold or to some foodstuffs like sugar. Variations in enamel is more than just the color. Some people are born with thin or no enamel on their teeth. Some people have pourous marks on their teeth.

Ligaments, Gingiva and TMJ joint:
The teeth are held in the bones of the jaws by ligaments called the periodontium and the bones and the necks of the teeth are covered by gum tissue (the gingiva). When they are healthy the ligaments are constantly tightening to keep the teeth together and to let you know how hard you need to bite when you’re chewing food. The jaw bones are called the maxilla (the top jaw) and the mandible (the bottom jaw). The mandible is a horseshoe shape and joins on to the base of the skull at the temporomandibular joints (TM joints), which lie directly in front of the ears. The TM joints have a cartilage like the knee joint and can occasionally click when you open and close your mouth but, although this may be annoying, it is often harmless. Harmful clicking is when your bite between maxillay and mandible does not fit together correctly creating pain. An orthodontist with a degree, rather than a certificate, is who should help with bite diagnosis. Braces, appliances or surgery may be necessary to correct bite and joint problems.

Teeth and Jaw Bone Growth:
Teeth and biting is what stimulates your jaw bones to grow. Without teeth, such as dentures only or just some missing teeth, the jaw bone is not stimulated to grow and people with dentures may say they do not fit anymore. They need a reline of the surface due to bone shrinkage. Most people think that there is something wrong with the denture. The denture and the dentist is not to blame! It is best to take care of your own teeth. If there is trauma or permanent teeth were not formed, the next best thing is to get a tooth implant. This will continue to stimulate bone and will generally last for 10 or more years with correct care.
Digestive system 2 - The Anatomy Wiki

Digestive system 2 - The Anatomy Wiki

Try out your skills with "The Tongue Twister Database!"

Tongue

Tongue
The tongue consists of four types of taste buds--salty, sweet, sour, and bitter--and is a very maneuverable and pliable arrangement of muscle. It helps to remove, and dislocate food particles in the teeth and shifts food around in the mouth in order to assist with the all important act of swallowing.

The act of swallowing food, which at this place in the system is called a bolus, brings many organs into action. As the top of your tongue presses up against the hard palate , the roof of your mouth, food is shoved to the back of the mouth. This action in turn brings the soft palate and uvula (the place at the very back of the mouth where there is a teardrop shape located) into action. They keep the food from being misguided toward the nose. Once past the soft palate, the food is in the pharynx, a train station with two tracks, one leading to the trachea (windpipe), the other to the esophagus (food tube). The epiglottis projects out from the trachea side and helps to admit free movement of air as it is swallowed and at the same time restricts entrance to the esophagus.

The larynx, provides the epiglottis with most of its muscle for movement. It applies an upward force that helps to relax some tension on the esophagus, so that food enters where it is meant to go, down the esophagus and not down the windpipe. Many people have experienced at some time or another when the swallowing action did not go as it was supposed to. Cough. Cough. Choke. The larynx is for sound production and commonly known as our voice box or vocal cords. It is surrounded by cartilage called thyroid cartilage that forms our "adam's apple".

Salivary Glands

Three pairs of major salivary glands (parotid, submandibular, and sublingual glands) and numerous smaller ones secrete saliva into the oral cavity, where it is mixed with food during mastication (chewing). Saliva contains water, mucus, and enzyme amylase. Functions of saliva include the following:
    • It has a cleansing action on the teeth.
    • It moistens and lubricates food during mastication and swallowing.
    • It dissolves certain molecules so that food can be tasted.
    • It begins the chemical digestion of starches through the action of amylase, which breaks down polysaccharides into disaccharides.

Digestive system 2 - The Anatomy Wiki





Anatomy of the pancreas:Anatomy of the biliary system

The pancreas is an elongated, tapered organ located across the back of the abdomen, behind the stomach and retroperitoneal. The right side of the organ (called the head) is the widest part of the organ and lies in the curve of the duodenum (the first section of the small intestine). The tapered left side extends slightly upward (called the body of the pancreas) and ends near the spleen (called the tail).
The pancreas is made up of two types of tissue:
  • exocrine tissue
    The exocrine tissue secretes digestive enzymes. These enzymes are secreted into a network of ducts that join the main pancreatic duct, which runs the length of the pancreas.
  • endocrine tissue
    The endocrine tissue, which consists of the islets of Langerhans, secretes hormones into the bloodstream.

Functions of the pancreas:

The pancreas has digestive and hormonal functions:
  • The enzymes secreted by the exocrine tissue in the pancreas help break down carbohydrates, fats, proteins, and acids in the duodenum. These enzymes travel down the pancreatic duct into the bile duct in an inactive form. When they enter the duodenum, they are activated. The exocrine tissue also secretes a bicarbonate to neutralize stomach acid in the duodenum.
  • The hormones secreted by the endocrine tissue in the pancreas are insulin and glucagon (which regulate the level of glucose in the blood), and somatostatin (which prevents the release of the other two hormones).


Anatomy of the liver:

The liver is located in the upper right-hand portion of the abdominal cavity, beneath the diaphragm and on top of the stomach, right kidney, and intestines. Shaped like a triangle, the liver is a dark reddish-brown organ that weighs about three pounds. It is also the largest internal organ of the body.
There are two distinct sources that supply blood to the liver:
  • oxygenated blood flows in from the hepatic artery
  • nutrient-rich blood flows in from the portal vein
The liver holds about one pint (13 percent) of the body's blood supply at any given moment.
The liver consists of two main lobes, both of which are made up of thousands of lobules divided by the falciform ligament. These lobules are the structural and functional units of the liver and are connected to small ducts that connect with larger ducts to ultimately form the hepatic duct. The hepatic duct transports the bile produced by the liver cells to the gallbladder and duodenum (the first part of the small intestine).

Functions of the liver:

Did you know ... The liver can lose three-quarters of its cells before it stops functioning?
In addition, the liver is the only organ in the body that can regenerate itself.
The liver regulates most chemical levels in the blood and excretes a product called "bile," which helps carry away waste products from the liver. All the blood leaving the stomach and intestines passes through the liver. The liver processes this blood and breaks down the nutrients and drugs into forms that are easier to use for the rest of the body. More than 500 vital functions have been identified with the liver. Some of the more well-known functions include:
  • Production of bile, which helps carry away waste and break down fats in the small intestine during digestion.
  • Production of certain proteins for blood plasma.
  • Production of cholesterol and special proteins to help carry fats through the body.
  • Conversion of excess glucose into glycogen for storage. (This glycogen can later be converted back to glucose for energy.)
  • Regulation of blood levels of amino acids, which form the building blocks of proteins.
  • Processing of hemoglobin for use of its iron content. (The liver stores iron.)
  • Conversion of poisonous ammonia to urea. (Urea is one of the end products of protein metabolism that is excreted in the urine.)
  • Filtering the blood of drugs and other poisonous substances.
  • Regulating blood clotting.
  • Resisting infections by producing immune factors and removing bacteria from the blood stream.
When the liver has broken down harmful substances, its by-products are excreted into the bile or blood. Bile by-products enter the intestine and ultimately leave the body in the feces. Blood by-products are filtered out by the kidneys, and leave the body in the form of urine.

Gallbladder

The gallbladder is a pear-shaped sac that is attached to the visceral surface of the liver by the cystic duct. The principal function of the gallbladder is to serve as a storage reservoir for bile. Bile is a yellowish-green fluid produced by liver cells. The main components of bile are water, bile salts, bile pigments, and cholesterol. The bile can then leave the gallbladder via the cystic duct which connects the the gallbladder to the common bile duct.
Blood is brought to the gallbladder by a branch of the hepatic artery and taken away by the hepatic portal vein.
Bile salts act as emulsifying agents in the digestion and absorption of fats. Cholesterol and bile pigments from the breakdown of hemoglobin are excreted from the body in the bile.

What are gallstones?

Gallstones form when liquid stored in the gallbladder hardens into pieces of stone-like material. The liquid, called bile, is used to help the body digest fats. Bile is made in the liver, then stored in the gallbladder until the body needs to digest fat. At that time, the gallbladder contracts and pushes the bile into a tube--called the common bile duct--that carries it to the small intestine, where it helps with digestion.
Bile contains water, cholesterol, fats, bile salts, proteins, and bilirubin. Bile salts break up fat, and bilirubin gives bile and stool a yellowish color. If the liquid bile contains too much cholesterol, bile salts, or bilirubin, under certain conditions it can harden into stones.

Here are some great links to help you study!
An Overview of the Pancreas
An Overview of the Stomach and Gallbladder
An Overview of the Liver
Virtual Body Tour through the Digestive System

Here is a video (from How Stuff Works) that shows the roles that the liver, gall bladder, and pancreas have in digestion.


Case Study
Neonatal Jaundice
Case Presentation
Martin and Kim were both twenty-five when they had Michael, their first child. Kim remained very healthy during her pregnancy and went into labor at 9:00 a.m., just 3 days after her due date. Delivery went quite smoothly, and that evening, mother and child rested comfortably. Two days later, Kim and Michael were released from the hospital. That evening at feeding time, Kim noticed that the whites of Michael’s eyes seemed just slightly yellow, a condition that worsened noticeably by the next morning. Kim called the pediatrician and made an appointment for that morning.
Upon examining Michael, the pediatrician informed Martin and Kim that the infant had neonatal jaundice, a condition quite common in newborns and one that need not cause them too much concern. The physician explained that neonatal jaundice was the result of the normal destruction of old or worn fetal red blood cells and the inability of the newborn’s liver to effectively process bilirubin, a chemical produced when red blood cells are destroyed. The physician told the parents he would like to see Michael every other day in order to monitor blood bilirubin concentration until the bilirubin concentration dropped into the normal range. He recommended that Kim feed Michael frequently and instructed them to place Michael in sunlight whenever possible.
Case Background
Neonatal jaundice in a disorder that affects nearly 50% of all newborns to at least a small degree. The yellow coloration of the skin and sclera of the eyes is due to the accumulation of bilirubin in adipose tissue and its adherence to collagen fibers. In neonatal jaundice, the excess bilirubin is not due to an abnormal level of red blood cell destruction. It is due to the inability of the young liver cells to conjugate bilirubin, or make it soluble in bile, so that it can be excreted and removed from the body by the digestive tract. This inability is corrected, usually within one week, as the liver cells synthesize the conjugation enzymes. If uncorrected, sufficiently high bilirubin concentrations can cause brain damage. Frequent feedings of a newborn with jaundice increase gastrointestinal tract motility and decrease the likelihood of reabsorbing significant amounts of bilirubin in the small intestine. Radiation from sunlight alters the chemical form of bilirubin, making is easier for the liver to excrete.

In the News

  • Here is an article that talks about how insulin-producing cells from the pancreas can regenerate stem-like cells.

Glossary
AmylaseAn enzyme that breaks down starch into sugar.
Pancreas: A spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.
Insulin:A hormone made by the islet cells of the pancreas. Insulin controls the amount of sugar in the blood.
Glucose: A form of sugar that is the body's primary fuel; glucose broken down from food can be converted into energy or stored.
Glucagon: A hormone made by the pancreas, It is released into the blood stream when blood sugar levels are low.
Salivary Glands: Located in the mouth. Within the salivary glands are two types of secretory cells, serous cells and mucous cells. The serous cells produce a watery fluid that contains a digestive juice called amylase. Amylase splits starch and glycerol into complex sugars. The mucous cells secrete a thick, sticky liquid called mucus. Mucus binds food particles together and acts to lubricate during swallowing. The fluids produced by the serous and mucous cells combine to form saliva. Approximately 1 liter of saliva is secreted daily.
Liver: The liver is the largest gland in the body. It is located in the upper abdomen on the right side, just under the diaphragm and superior to the duodenum and pylorus that secretes bile and is active in the formation of certain blood proteins and in the metabolism of carbohydrates, fats, and proteins.
Gallbladder: The gallbladder is a pear-shaped sac, usually stained dark green by the bile it contains. It is located in the hollow underside of the liver. Its duct, the cystic duct, joins the hepatic duct from the liver to form the common bile duct, which enters the duodenum. The gallbladder receives bile from the liver and then concentrates and stores it. It secretes bile when the small intestine is stimulated by the entrance of fats.
Exocrine Tissue: Tissue of the pancreas. Secretes the digestive enzymes to help break down carbohydrates, fats, proteins, and acids in the duodenum.
Endocrine Tissue: Tissue of the pancreas. Secretes the hormones insulin, glucagon, and somatostatin into the blood stream.
Tongue (lower surface): fleshy, mobile organ situated in the mouth of humans, used to taste, swallow and speak.
Superior dental arch: set of teeth of the upper jaw.
Sublingual fringe: fringe beneath the tongue.
Lingual vein: vein of the tongue.
Sublingual protuberance: a projection under the teeth.
Openings of the ducts of the submandibular and sublingual salivary glands: papillae situated beneath the tongue.
Lower lip: lower external part of the mouth, covering the tongue.
Frenulum of the tongue: membrane that prevents a person from swallowing his or her tongue.
Upper lip: upper external part of the mouth, covering the teeth
.

Connections to other body systems
Digestive system 1
Circulatory System
The Brain
Review Questions

1. The _________ secretes digestive enzymes and bicarbonate solution into the small intestine to aid digestion.
a. pancreas
b. gallbladder
c. liver
d. all of the above are correct

2. Which of the following represents the action of insulin?
a. increases blood glucose levels by the hydrolysis of glycogen
b. decreases blood glucose levels by stimulating glucagon production
c. decreases blood glucose levels by forming glycogen
d. increases blood glucose levels by promoting cellular uptake of glucose

3. An accessory organ that stores nutrients, detoxifies the blood, and regulates blood glucose levels is called the ______.
a. liver
b. spleen
c. pancreas
d. duodenum

4. What organ secretes enzymes in an inactive form?
a. liver
b. pancreas
c. gallbladder
d. salivary glands

5. What's the name and function of the enzyme found in saliva?
a. lipase, which promotes fat digestion
b. amylase, which initiates starch digestion
c. pepsinogen, which initiates protein digestion
d. rennin, which promotes milk protein digestion

6. The Ph of food entering the duodenum is changed from acidic to alkaline by _______?
a. gastric juices
b. bile pigments
c. intestinal enzymes
d. pancreatic secretions

7. Which food would be hard to digest if a person's gallbladder was removed?
a. fat
b. starch
c. protein
d. fatty acid

8. Bile salts are needed for the optimum effectiveness of what?
a. lipase
b. amylase
c. pepsinogen
d. protein

9. The accessory glands that pour secretions into the digestive system to facilitate digestion include?
a. salivary glands, gallbladder, pancreas
b. pharynx, esophagus, large intestine
c. appendix, stomach, duodenum
d. liver, colon, mouth

10. What are the functions of the salivary glands?
a. cleanses the mouth
b. contains enzymes that begin in the chemical breakdown of starchy foods
c. moistens food and aids in compacting it into a bolus
d. all of the above

Answers: 1. a, 2. c, 3. a, 4. b, 5. b, 6. d, 7. a, 8. a,9. a, 10. d



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